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Rho family of GTPases

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Terminological databases

Rakubioloogia terminibaas

ID 460947 Last modified 01.06.2023
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  • monomeersete GTPaaside perekond, kuhu kuulub Ras suurperekond, mille liikmed reguleerivad signaliseerimise käigus tsütoskeleti ümberkorraldumist
  • The Rho family of GTPases is a family of small (~21 kDa) signaling G proteins, and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have been shown to regulate many aspects of intracellular actin dynamics, and are found in all eukaryotic kingdoms, including yeasts and some plants. Three members of the family have been studied in detail: Cdc42, Rac1, and RhoA. All G proteins are "molecular switches", and Rho proteins play a role in organelle development, cytoskeletal dynamics, cell movement, and other common cellular functions.
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  • Siia kuuluvad Rho, Rac ja Cdc42.
Rho family of GTPases

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