a chain of enzymatic reactions, each link producing a product that is a substrate in the next link. A pathway may produce energy (e.g., the citric acid cycle) or some structural product (e.g., fatty acid or glycogen).
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FI: aineenvaihduntatie [U50421]; aineenvaihduntareitti [EUR]
FR: voie métabolique [U50421]
DE: der Stoffwechselweg [U50421]; metaboler Weg [EUR]
Study of metabolism,
- metabolic balance: rate and extent of absorption and elimination of the active substance,
- identification of the metabolic pathways and main metabolites,
- distribution and excretion (biliary, urinary, faecal) of the metabolites,
- if appropriate, influence of the intestinal or ruminal microflora, of enterohepatic cycle, of caecotrophy, on the metabolism.
