an acute inflammatory condition of the skin following topical exposure to an allergen to which the subject shows delayed hypersensitivity, an allergic response following direct contact of an allergen (such as latex, nickel, or poison ivy) with the skin that is typically marked by an itchy red rash often accompanied by swelling and watery blisters, a delayed type IV allergic reaction of the skin with varying degrees of erythema, edema, and vesiculation resulting from cutaneous contact with a specific allergen