Transderm-V (scopolamine) transdermal therapeutic system is a circular flat unit designed for continuous release of scopolamine following application to an area of intact skin behind the ear ... An initial priming dose of scopolamine, released from the adhesive layer of the system, saturates the skin binding sites for the drug and brings the plasma concentration to the required steady-state level. Subsequently, there is continuous controlled release of scopolamine, from the drug reservoir through the rate controlling membrane.
Researchers who would like to deliver other drugs with transdermals are tackling a more general problem. ... There a thin reservoir of medicine is released steadily through a plastic membrane to the skin where it travels in the bloodstream.
