Murdetegurimõõtureid kasutatakse sageli kõrgefektiivse vedelikkromatograafia detektoritena, kuna neid peetakse universaalseteks detektoriteks, sest nad suudavad tuvastada ja mõõta kõike, mille murdumistegur erineb lahusti murdumistegurist, kuid tundlikkus on madal.
They are often used as detectors forhigh-performance liquid chromatography and size exclusion chromatography. They are considered to be universal detectors because they can detect anything with a refractive index different from the solvent, but they have low sensitivity.