aine mürgisisaldus, mis surmab pool katseorganismidest
the concentration of material in air, water, soil or sediment to which test organisms are exposed which is estimated to be lethal to 50 % of the test organisms
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FI: keskimääräinen tappava pitoisuus [T50879]
DE: mittlere Letalkonzentration [T50879]; mittlere tödliche Konzentration, LC [ENV]
FR: concentration létale médiane [T50879]
The PNEC shall be calculated by applying an assessment factor to the values resulting from tests on organisms, e.g. LD50 (median lethal dose), LC50 (median lethal concentration), EC50 (median effective concentration), IC50 (concentration causing 50 % inhibition of a given parameter, e.g. growth), NOEL(C) (no-observed-effect level(concentration)), or LOEL(C) (lowest-observed-effect level (concentration)).
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