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haemophilia

1

Terminological databases

EKI terminibaas Esterm

ID 737123 Last modified 27.12.2018
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Domain haemopathology
  • ühe või mitme hüübimisteguri kaasasündinud vaegusel või hüpofunktsioonil põhinev veritsustõbi, mille sümptomiteks on verejooksud pehmetesse kudedesse ja liigestesse ning haavade kauakestev veritsus
  • a hereditary hemorrhagic diathesis characterized by haemarthrosis and deep tissue bleeding, due to deficient generation of intrinsic thromboplastin
  • a hereditary, sex-linked blood defect occurring almost exclusively in males that is marked by delayed clotting of the blood with prolonged or excessive internal or external bleeding after injury or surgery and in severe cases spontaneous bleeding into joints and muscles and that is caused by a deficiency of clotting factors
Good to know
  • Hemophilia is inherited as an X-linked recessive trait in which the mother must pass on a copy of the defective gene to a male child, and more rarely, both parents must pass on copies of the defective gene to a female child.
hemofiilia
Usage examples
  • Kõige sagedasem (80–90% hemofiiliajuhtudest) on A-hemofiilia, mille korral puudub või on vähenenud VIII hüübimisteguri süntees. ... Verejooksude peatamiseks kasutatakse asendusravi VIII hüübimisteguri kontsentraadiga, mille annus sõltub selle teguri puuduse astmest ja verejooksu iseloomust. ... B-hemofiiliat (IX hüübimisteguri puudus või vähesus) esineb harvem – üks juht 30 000 poisslapse sünni kohta. Haigust kandva geeni muutus pärandub samuti naissugukromosoomiga ning B-hemofiilia sümptomid on samasugused kui A-hemofiilial. Verejooks peatatakse IX hüübimisteguri kontsentraadi abil.
haemophilia
Usage examples
  • This includes Parkinson’s disease, Multiple Sclerosis, Epilepsy, Amyotrophic lateral sclerosis, Attention Deficit Hyperactivity Disorders, Cognitive retardation and disruption of motor, perceptual, language and socio-emotional functions, haematological diseases (including haemophilia), immunological disorders, allergies except asthma, genito-urinary diseases, gastroenterological diseases, endocrinological diseases, ear, nose and throat disorders, ophthalmology disorders and dermatology diseases as well as diseases related to environmental factors.
Good to know
  • chiefly British
hemophilia
haemophilia

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