en

denaturation

1

Terminological databases

EKI terminibaas Esterm

ID 720840 Last modified 30.12.2004
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Domain Chemistry
  • a change in conformation and a loss of secondary and tertiary structure due to the loss of non-covalent bonding that occurs when proteins and nucleic acids are exposed to extreme temperature or pH, non physiological concentrations of salt, detergents, organic solvents or other chemical agents. It can lead to unfolding of the polypeptide chain in proteins and dissociation of the helical structure in nucleic acids. The changes may be associated with modifications in solubility,physical properties and biological activity. The process may be reversible.
denaturatsioon
denaturation
Usage examples
  • sandwich immunoassay for PrP Res carried out following denaturation and concentration steps (Bio-Rad Platelia test)
dénaturation
Denaturierung
denaturointi

Biokeemiasõnastik

ID 457281 Last modified 13.09.2019
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Geneetika terminibaas

ID 1152645 Last modified 05.01.2026
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  • protsess, kus valgu makromolekul kaotab oma loomuliku konformatsiooni
denaturatsioon
Good to know
  • Denaturatsiooni tulemusena kaob tavaliselt ka valgu bioloogiline aktiivsus. Kui DNA kaksikahelast tekkivad üksikahelalised DNA molekulid, võivad nad hiljem hiljem oma struktuuri taastada renaturatsiooni käigus.
denaturation

Loomakasvatuse terminibaas

ID 478007 Last modified 16.06.2021
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  • biopolümeeride, peamiselt valkude, omaduste muutmine keemiliste või füüsikaliste protsesside tulemusena

Tuumaenergia ja kiirguskaitse terminibaas

ID 584612 Last modified 15.12.2022
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Domain Nuclear Technology & Nuclear Industrynuclear safeguards system - safeguardsradioactive materials
  • protsess, mida viiakse läbi lõhustuvate materjalidega, mis sobivad tuumapommi jaoks ja mille tagajärjel on see materjal muundatud kujule, mis ei sobi kasutamiseks tuumapommides ja mille tagasi muundamine ei ole lihtsate meetoditega võimalik
  • (denaturation) of fissile materials suitable for nuclear weapons is the process of transforming them into a form that is not suitable for weapons use and can not easily be reversely transformed

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