väga konserveerunud seriin/treoniin/türosiin proteiin kinaaside perekond, mille liikmed osalevad paljude rakkudes toimuvate protsesside reguleerimises, nagu seda on rakujagunemine, diferentseerumine, liikumine, stressi vastuse kujunemine, apoptoos ning elus püsimine, A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine, threonine, and tyrosine (i.e., a serine/threonine-specific protein kinase). MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis.