Spetsiifilise toimeainena sisaldub puuvillaseemnetes gossüpoli (0,15…1,59%), mis on loomadele mürgine. Seemnete töötlemisel osa gossüpolist seotakse, mistõttu kookides ja srottides on seda vähe, kuid organismi koguneva mürgina võib ta pikapeale loomade tervisele mõjuda.
The pressed cake from the production of cottonseed oil must also be processed to remove a toxic pigment, gossypol, before it can be used as feed for nonruminant livestock such as pigs and poultry.
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