rakutuumas paiknevad intermediaarseid filamente moodustavad valgud, Nuclear lamins interact with membrane-associated proteins to form the nuclear lamina on the interior of the nuclear envelope., Расположенные в ядре белки, образующие промежуточные филаменты. Ламины образуют под ядерной мембраной особую фибриллярную сеть, которая называется ядерной ламиной и поддерживает структуру ядра., intermediaarsete filamentide hulka kuuluvad valgud, mis moodustavad tuuma laamina, Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact with membrane-associated proteins to form the nuclear lamina on the interior of the nuclear envelope. Lamins are present in all members of the kingdom Animalia (Metazoa), but are not found in unicellular organisms, plants, or fungi. Lamin proteins are involved in the disassembling and reforming of the nuclear envelope during mitosis, the positioning of nuclear pores, and programmed cell death. Mutations in lamin genes can result in laminopathies, some of which are potentially lethal disorders.