aine vähim sisaldus tootes, mis on toksisustestis katseorganismidele negatiivset mõju avaldanud
the lowest concentration of a material used in a toxicity test that has a statistically significant adverse effect on the exposed population of test organisms compared with the controls
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FI: heikoin annos (pitoisuus), joka aiheuttaa havaittavan vaikutuksen [T50879]; pienin havaittavan vaikutksen pitoisuus, LOEC [ENV]
DE: geringste Dosiskonzentration, bei der eine Wirkung beobachtet wird [T50879]; unterste Konzentration mit erkennbarem Effekt [ENV]
FR: dose (concentration) la plus faible entra?nant l'effet observé [T50879]
The PNEC shall be calculated by applying an assessment factor to the values resulting from tests on organisms, e.g. LD50 (median lethal dose), LC50 (median lethal concentration), EC50 (median effective concentration), IC50 (concentration causing 50 % inhibition of a given parameter, e.g. growth), NOEL(C) (no-observed-effect level(concentration)), or LOEL(C) (lowest-observed-effect level (concentration)).
