the separation of the isotopes of an element from each other on the basis of slight differences in their physical properties
the process of concentrating specific isotopes of a chemical element by removing other isotopes, for example separating natural uranium into enriched uranium and depleted uranium
There are three types of isotope separation techniques: Those based directly on the atomic weight of the isotope. Those based on the small differences in chemical reaction rates produced by different atomic weights. Those based on properties not directly connected to atomic weight, such as nuclear resonances.
This Agreement shall apply to: ... all forms of nuclear material prepared by chemical or physical processes or isotopic separation provided that the quantity of nuclear material so prepared shall only be regarded as falling within the scope of this Agreement in the same proportion as the quantity of nuclear material used in its preparation, and which is subject to this Agreement, bears to the total quantity of nuclear material so used.