The majority of substances to be registered under REACH will require a full set of physico-chemical data depicting physico-chemical properties. Physico-chemical data are used to assess the physical hazards (e.g. flammability) and help predict possible toxicological or environmental hazards, fate and behaviour. They are used mainly for the purposes of safe handling but also, in the determination of the risk posed to humans and the environment from all stages of a substance lifecycle (see table Impacts and uses of physico-chemical data under REACH).